STRATA - SerTRaline for AnxieTy in adults with a diagnosis of Autism. A randomised controlled trial

What is this study about?

STRATA study is the largest study on the treatment of anxiety in autistic people. STRATA aims to find out whether the medication sertraline is an effective treatment for anxiety in adults with a diagnosis of autism. STRATA has been co-produced with experienced clinicians, researchers, and autistic people. You can take part from anywhere in the UK.

Who can take part?

Adults with a diagnosis of autism and have (or had) symptoms of anxiety.

What is involved?

Participants will receive either sertraline, or a placebo (inactive) medication which they will be asked to take for up to one year. Participants will be contacted briefly via video call, telephone, text or email (whichever they prefer) 4 times in the first 4 months, and again after 9 months to see how they are getting on with the medication. Participants will also complete questionnaires about their anxiety and other symptoms at the start of the study, and after 4 months, 6 months, and 1 year, and will be offered a £10 gift voucher for completing these

How to get involved?

Please contact Eleni Tsappis by email at for more information.